Chaohua Lin Selected Research

Osteoarthritis

1/2016	Identification of potent and selective retinoic acid receptor gamma (RARγ) antagonists for the treatment of osteoarthritis pain using structure based drug design.
12/2014	Identification of potent and selective hydantoin inhibitors of aggrecanase-1 and aggrecanase-2 that are efficacious in both chemical and surgical models of osteoarthritis.

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Chaohua Lin Research Topics

Disease

3	Arthritis (Polyarthritis) 01/2017 - 03/2016
3	Pain (Aches) 05/2016 - 01/2016
2	Inflammation (Inflammations) 01/2017 - 03/2016
2	Arthralgia (Joint Pain) 03/2016 - 01/2016
2	Osteoarthritis 01/2016 - 12/2014
1	Autoimmune Diseases (Autoimmune Disease) 10/2023
1	Hemorrhage 03/2016
1	Myocardial Infarction 03/2016

Drug/Important Bio-Agent (IBA)

2	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 01/2017 - 05/2016
2	Dinoprostone (PGE2)FDA Link 01/2017 - 03/2016
2	ProstaglandinsIBA 01/2017 - 03/2016
2	EnzymesIBA 03/2016 - 12/2014
1	Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA 01/2017
1	Prostaglandins EIBA 01/2017
1	Iodoacetic AcidIBA 05/2016
1	Diclofenac (SR 38)FDA LinkGeneric 05/2016
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 03/2016
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 03/2016
1	Retinoic Acid Receptor gammaIBA 01/2016
1	LY2955303IBA 01/2016
1	ADAMTS5 ProteinIBA 12/2014
1	ADAMTS4 ProteinIBA 12/2014
1	HydantoinsIBA 12/2014

Therapy/Procedure

2	Therapeutics 10/2023 - 12/2014
1	Analgesia 01/2017